Spoutable creates multiple strategies based on the placements you select for each Zone of your site. These strategies are tested and promoted via machine learning to maximize your site RPM. Generally the more placements you enable, the higher the revenue potential. 

Spoutable algorithms also test a variety of ads within these placements based on the Category you select for your site, and promote the ads that perform best in terms of eCPM (a combination of cost per click and user engagement).

Initial optimization can take around three days, but our algorithms are continually adjusting settings to account for new units, advertisers and changes that occur on a site over time. 

Related Articles: 
Which Zones on my site can I monetize with Spoutable?
How do I customize placements for each Zone of my site?
How can I increase the eCPM I earn from Spoutable?